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| Kurt Russell | Snake Plissken |
| Ernest Borgnine | Cabbie |
| Adrienne Barbeau | Maggie |
| Lee Van Cleef | Bob Hauk |
| Donald Pleasence | President of the United States |
| Isaac Hayes | The Duke of New York |
| Season Hubley | Girl in Chock Full O'Nuts |
| Harry Dean Stanton | Harold 'Brain' Helman |
| Tom Atkins | Rehme |
| Charles Cyphers | Secretary of State |
A hardened criminal is offered a pardon if he rescues the president from convicts in the prison city of Manhattan.
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