| Natasha Henstridge | Lorna |
| Luke Wilson | Andy |
| Kathleen Robertson | Cheryl |
| Janeane Garofalo | Jeri |
| Bruce McCulloch | Jeff |
| Kristin Lehman | Keiran |
| Amie Carey | Rachel |
| Gordon Currie | Trevor |
| Harland Williams | Callum |
| Mark McKinney | Dr. Cavan, Dog Psychologist |
| Jerry Schaefer | Norm |
| Zachary Bennett | Dougie |
| Peter MacNeill | Neighbor |
Andy, a frequenter of a local dog park, experiences a series of breakups, betrayals and flings. First, his girlfriend, Cheryl, leaves him for another man and takes the couple's loyal dog with her. Then, he meets TV personality Lorna, but she's so preoccupied with her own canine pal that she has little time for love. Andy soon realizes that he prefers the company of man's best friend over women -- but romance isn't done with him yet.
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