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| Vince Vaughn | Peter LaFleur |
| Christine Taylor | Kate |
| Ben Stiller | White Goodman |
| Rip Torn | Patches O'Houlihan) |
| Justin Long | Justin |
| Stephen Root | Gordon |
| Joel Moore | Owen |
| Chris Williams | Dwight |
| Alan Tudyk | Steve the Pirate |
| Missi Pyle | Fran |
| Jamal E. Duff | Me'Shell Jones |
| Gary Cole | |
| Jason Bateman | |
| Hank Azaria | |
| Al Kaplon | |
| Lance Armstrong | |
| Chuck Norris | |
| William Shatner | |
| David Hasselhoff |
The owner of a gym and an overbearing entrepreneur form dodgeball teams to compete for $50,000 in Las Vegas.
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