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| Tom Cruise | Cole Trickle |
| Robert Duvall | Harry Hogge |
| Nicole Kidman | Dr. Claire Lewicki |
| Randy Quaid | Tim Daland |
| Michael Rooker | Rowdy Burns |
| Cary Elwes | Russ Wheeler |
| Fred Dalton Thompson | Big John |
| John C. Reilly | Buck Bretherton |
| J.C. Quinn | Waddell |
| Don Simpson | Aldo Bennedetti |
| James Martin Jr. | Field Doctor |
In the fast-paced world of NASCAR, a rivalry brews between rookie hotshot Cole Trickle and veteran racer Rowdy Burns . When both of them are seriously injured in competition, the former bitter rivals become close friends. With Cole's spirits restored by a romance with neurosurgeon Dr. Claire Lewicki, and Rowdy still sidelined by injuries, Cole decides to race Rowdy's car in the Daytona 500 against underhanded newcomer Russ Wheeler .
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