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| Dana Andrews | Dr. John Holden |
| Peggy Cummins | Joanna Harrington |
| Niall MacGinnis | Dr. Julian Karswell |
| Maurice Denham | Professor Henry Harrington |
| Athene Seyler | Mrs. Karswell |
| Liam Redmond | Professor Mark O'Brien |
| Reginald Beckwith | Mr. Meek |
| Ewan Roberts | Lloyd Williamson |
| Peter Elliott | Professor K.T. Kumar |
| Rosamund Greenwood | Mrs. Meek |
| Richard Leech | Inspector Mottrarn |
| Lloyd Lamble | Detective Simmons |
| Peter Hobbs | Superintendent |
| Charles Lloyd Pack | Chemist |
| John Salew | Librarian |
| Percy Herbert | Farmer (deleted from US print) |
American professor John Holden arrives in London for a conference on parapsychology only to discover that the colleague he was supposed to meet was killed in a freak accident the day before. It turns out that the deceased had been investigating a cult lead by Dr. Julian Karswell . Though a skeptic, Holden is suspicious of the devil-worshiping Karswell. Following a trail of mysterious manuscripts, Holden enters a world that makes him question his faith in science.
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