| Jason Statham | Chev |
| Amy Smart | Eve |
| Jose Pablo Cantillo | Ricky Verona |
| Efren Ramirez | Kaylo |
| Dwight Yoakam | Doc Miles |
| Carlos Sanz | Carlito |
| Jay Xcala | Alex |
| Keone Young | Don Kim |
| Reno Wilson | Orlando |
Chev Chelios, a hit man wanting to go straight, lets his latest target slip away, then he awakes the next morning to a phone call that informs him he has been poisoned and has only an hour to live unless he keeps adrenaline coursing through his body while he searches for an antidote.
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