| Tom Hanks | Zachry, et al |
| Halle Berry | Luisa Rey, et al |
| Jim Broadbent | Timothy Cavendish, et al |
| Hugo Weaving | Nurse Noakes, et al |
| Jim Sturgess | Adam Ewing, et al |
| Doona Bae | Sonmi-451, et al |
| Ben Whishaw | Robert Frobischer, et al |
| James D'Arcy | Rufus Sixsmith, et al |
| Susan Sarandon | Madame Horrox, et al |
| Hugh Grant | Kona Chief, et al |
| Keith David | Joe Napier, et al |
| Xun Zhou | Yoona-930, et al |
| David Gyasi | Autua, et al |
| Robert Fyfe | Old Salty Dog, et al |
| Martin Wuttke | Mr. Boerhaave, et al |
| Robin Morrissey | Young Cavendish |
| Brody Lee | Javier Gomez, et al |
More Cloud Atlas Pictures
Actors take on multiple roles in an epic that spans five centuries. An attorney harbors a fleeing slave on a voyage from the Pacific Islands in 1849; a poor composer in pre-World War II Britain struggles to finish his magnum opus before a past act catches up with him; a genetically engineered worker in 2144 feels the forbidden stirring of human consciousness -- and so on. As souls are born and reborn, they renew their bonds to one another throughout time.