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| Harrison Ford | Jack Ryan |
| Willem Dafoe | John Clark |
| Anne Archer | Cathy Muller Ryan |
| Joaquim de Almeida | Col. Felix Cortez |
| Henry Czerny | Robert Ritter |
| Harris Yulin | James Cutter |
| Donald Moffat | President Bennett |
| Miguel Sandoval | Ernesto Escobedo |
| Benjamin Bratt | Captain Ramirez |
| Raymond Cruz | Domingo Chavez |
| Dean Jones | Judge Moore |
| Thora Birch | Sally Ryan |
| Ann Magnuson | Moira Wolfson |
| Hope Lange | Senator Mayo |
| Tom Tammi | FBI Director Emile Jacobs |
| Tim Grimm | FBI Agent Dan Murray |
| Belita Moreno | Jean Fowler |
| James Earl Jones | Adm. James Greer |
An acting CIA chief learns the president has triggered a war with Colombian drug cartels.
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