| Cuba Gooding Jr. | Arlo |
| Skeet Ulrich | Tim Mason |
| Peter Firth | Col. Andrew Brynner |
| David Paymer | Dr. Richard Long |
| Hudson Leick | Vaughn |
| Daniel Hugh Kelly | Col. Leo Vitelli |
| Kevin J. O'Connor | Telstar |
| Judson Mills | Dennis |
| Jordan Mott | Carl |
| Dwayne Macopson | Burke |
| Jim Grimshaw | Deputy Pappas |
| Tommy Smeltzer | Deputy Art Lewis |
| Bob Penny | Motel Manager |
Two men must prevent terrorists from taking a biological weapon and must keep the chemical's temperature below 50 F.
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