|Ben Affleck||Holden McNeil|
|Joey Lauren Adams||Alyssa Jones|
|Jason Lee||Banky Edwards|
|Dwight Ewell||Hooper LaMont|
|Jason Mewes||Jay Phat Buds/Chronic|
|Kevin Smith||Silent Bob/Bluntman|
|Casey Affleck||Little Kid|
Holden and Banky are best friends and authors of a popular comic book. Holden falls in love with Alyssa, who happens to be a lesbian. Holden's relationship with Alyssa strains his life-long friendship with Banky, and soon the relationship between Holden and Alyssa has problems when he cannot deal with her past.