|Will Ferrell||Armando Alvarez|
|Gael García Bernal||Onza|
|Nick Offerman||Agent Parker|
|Pedro Armendáriz Jr.||Miguel Ernesto Alvarez|
|John A. Lorenz||Aztec|
Armando's younger brother, Raul, returns to the family ranch with his beautiful fiancee, Sonia, and promises to fix its financial problems. Trouble soon follows when Armando falls in love with Sonia, and they discover Raul's business dealings are less than legitimate. All hell breaks loose when the most feared drug lord in Mexico, Onza, declares war on Raul and the rest of the family.