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| Jamie Foxx | Quincy Watson |
| Gabrielle Union | Nicky Callas |
| Morris Chestnut | Evan Fields |
| Peter MacNicol | Philip Gascon |
| Jennifer Esposito | Rita Monroe |
| Bianca Lawson | Helen Sharp |
| Jill Ritchie | Amy |
| Heather Headley | Herself |
| Robert J. Stephenson | Ticket Master |
| Samantha Nagel | Sandra/Executive Assistant |
| Grace Chan | Secretary |
Complications arise after a man writes a successful how-to book on ending romantic relationships.
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