| Gene Hackman | Sam Clayton |
| Candice Bergen | Miss Jones |
| James Coburn | Luke Matthews |
| Ben Johnson | Mister |
| Ian Bannen | Norfolk |
| Jan-Michael Vincent | Carbo |
| Mario Arteaga | Mexican |
| Robert Donner | Reporter |
| Robert Hoy | Lee Christie |
| Paul Stewart | J.B. Parker (uncredited) |
| Jean Willes | Rosie |
| John McLiam | Gebhardt |
| Dabney Coleman | Jack Parker |
| Jerry Gatlin | The Wood Cutter |
| Sally Kirkland | Honey |
| Walter Scott Jr. | Steve |
Ex-Rough Riders, an ex-prostitute and a gunfighter enter a marathon horse race across the desert.
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