| Bette Midler | Sadie Ratliff/Sadie Shelton |
| Lily Tomlin | Rose Ratliff/Rose Shelton |
| Fred Ward | Roone Dimmick |
| Edward Herrmann | Graham Sherbourne |
| Michele Placido | Fabio Alberici |
| Daniel Gerroll | Chuck |
| Barry Primus | Michael |
| Michael Gross | Doctor Jay Marshall |
| Deborah Rush | Binky Shelton |
| Nicolas Coster | Hunt Shelton |
| Patricia Gaul | Iona Ratliff |
| J.C. Quinn | Garth Ratliff |
| Norma Macmillan | Nanny Lewis |
| Joe Grifasi | Desk Clerk |
| John Vickery | Hotel Manager |
| John Hancock | Older Harlan |
| Mary Gross | Judy |
| Seth Green | Jason |
Two sets of twins born in the small town of Jupiter Hollow are mixed up by a confused nurse. The parents -- one set poor local farmers, the other wealthy socialites just passing through -- are none the wiser and take the twins home. Now, some 40 years later, the wealthy pair are involved in a business deal to buy and close down a factory in Jupiter Hollow. Hearing the news, the other set of twins travels to New York City to try and stop the sale.
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