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| Michael Hitchcock | Hamilton Swan |
| Parker Posey | Meg Swan |
| Eugene Levy | Gerry Fleck |
| Catherine O'Hara | Cookie Fleck |
| Christopher Guest | Harlan Pepper |
| John Michael Higgins | Scott |
| Michael McKean | Stefan |
| Jennifer Coolidge | Sheri Ann Cabot |
| Jane Lynch | Christy Cummings |
| Fred Willard | Buck Laughlin |
| Bob Balaban | Dr. Theodore W. Millbank, III |
| Ed Begley Jr. | Mark Schaefer, Hotel Manager |
| Patrick Cranshaw | Leslie Ward Cabot |
| Don Lake | Graham Chissolm |
| Jim Piddick | Trevor Beckwith |
| Larry Miller | Max Berman |
Pampered pooches and their quirky owners converge on Philadelphia to compete in a prestigious dog show.
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