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| Clint Eastwood | Philo Beddoe |
| Sondra Locke | Lynn Halsey-Taylor |
| Ruth Gordon | Senovia 'Ma' Boggs |
| Geoffrey Lewis | Orville Boggs |
| William Smith | Jack Wilson |
| Harry Guardino | James Beekman |
| Michael Cavanaugh | Patrick Scarfe |
| Barry Corbin | Fat Zack |
| Roy Jenson | Moody, Black Widow |
| Bill McKinney | Dallas, Black Widow |
| William O'Connell | Elmo, Black Widow |
| John Quade | Cholla, Black Widow Leader |
| Al Ruscio | Tony Rapoli Sr. aka Big Tony |
| Dan Vadis | Frank |
| Glen Campbell | Singer at Lion Dollar Cowboy Bar |
| Dick Christie | Jackson Officer |
| Anne Ramsey | Loretta Quince |
| Logan Ramsey | Luther Quince |
| Jim Stafford | Long John |
A bare-knuckle brawler battles crooks with his orangutan, girlfriend, buddy and mother .
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