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| William Hurt | Professor Eddie Jessup |
| Blair Brown | Emily Jessup |
| Bob Balaban | Arthur Rosenberg |
| Charles Haid | Mason Parrish |
| Thaao Penghlis | Prof. Eduardo Eccheverria |
| Miguel Godreau | Primal Man |
| Dori Brenner | Sylvia Rosenberg |
| Peter Brandon | Alan Hobart |
| Charles White Eagle | The Brujo |
| Drew Barrymore | Margaret Jessup |
| Megan Jeffers | Grace Jessup |
A psychophysiologist experiments with drugs and a sensory-deprivation tank and has visions he believes are genetic memories.
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