| Evan Rachel Wood | Lucy |
| Jim Sturgess | Jude |
| Joe Anderson | Max Carrigan |
| Dana Fuchs | Sadie |
| Martin Luther McCoy | Jo-Jo |
| T.V. Carpio | Prudence |
| Eddie Izzard | Mr. Kite |
| Bono | Dr. Robert |
| Salma Hayek | Singing Nurse |
| Spencer Liff | Daniel |
| Nicholas Lumley | Cyril |
| Michael Ryan | Phil |
| Bill Irwin | Uncle Teddy |
| Harry Lennix | Army Sergeant |
Songs by the Beatles illustrate a tale of two star-crossed lovers swept up by the 1960s counterculture and the anti-war movement.
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