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| Cillian Murphy | Jim |
| Noah Huntley | Mark |
| Naomie Harris | Selena |
| Brendan Gleeson | Frank |
| Megan Burns | Hannah |
| Christopher Eccleston | Henry |
| Marvin Campbell | Private Mailer |
| Sanjay Rambaruth | Private Davis |
| Ray Panthaki | Private Bedford |
| Junior Laniyan | Private Bell |
| Leo Bill | Private Jones |
| Ricci Harnett | Corporal Mitchell |
| Stuart McQuarrie | Sergeant Farrell |
| Luke Mably | Private Clifton |
| Justin Hackney | Infected Kid |
| Kim McGarrity | Mr. Bridges' Daughter |
| Alexander Delamere | Mr. Bridges |
| Emma Hitching | Jim's Mother |
| Christopher Dunne | Jim's Father |
| Toby Sedgwick | Infected Priest |
A group of misguided animal rights activists free a caged chimp infected with the ''Rage'' virus from a medical research lab. When London bike courier Jim wakes up from a coma a month after, he finds his city all but deserted. On the run from the zombie-like victims of the Rage, Jim stumbles upon a group of survivors, including Selena and cab driver Frank, and joins them on a perilous journey to what he hopes will be safety.
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