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| Sean Penn | Paul Rivers |
| Benicio Del Toro | Jack Jordan |
| Naomi Watts | Cristina Peck |
| Charlotte Gainsbourg | Mary Rivers |
| Melissa Leo | Marianne Jordan |
| Clea DuVall | Claudia |
| Danny Huston | Michael |
| Paul Calderon | Brown |
| Carly Nahon | Cathy |
| Claire Pakis | Laura |
In a film that plays with the idea of straightforward storytelling, a group of troubled people find that they are linked in unpredictable ways. Paul Rivers is an academic dealing with a terminal heart condition, but his life is changed by a car crash that seems unrelated to his ailment. The traffic accident, involving ex-con Jack Jordan and the husband of Cristina Peck, is one that ruins lives but ultimately also resurrects them.
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