|Glenn Close||Cruella De Vil|
|Jeff Daniels||Roger Darling|
|Joely Richardson||Anita Darling|
Fashion designer Anita and computer-game writer Roger meet, fall in love and marry along with their dalmatians Perdita and Pongo. The dogs' puppies are kidnapped by Anita's boss Cruella De Vil, who is stealing young dalmatians to make the coat she has set her heart on. Pongo and Perdita set out to find and rescue all ninety-nine pups from their fearsome captors.